This book explores the history of leading national universities in Asia and contemplates their capacity for innovation by focusing on the New Flagship University model. This model, presented more fully in The Flagship University Model—Changing the Paradigm from Global Ranking to National Relevancy (2016), envisions the university as an institution that not only meets the standards of excellence focused on research productivity and rankings, but one that is creatively responsive to the larger social needs of their specific national or regional environment and people. Chapters discuss the mission, policies and practices of the holistic and aspirational New Flagship University model and explore the contemporary academic cultures and innovations of leading national universities in China, Singapore, South Korea, Japan, India, and elsewhere. Each is pursuing aspects of the Flagship model on their own terms. Academic leaders and ministries in Asia are beginning to understand that the bell-curve approach of rankings and the myopic notion of a “World Class University” no longer provide an adequate strategy to guide policy, funding, and practice. This book furthers discussions within universities about their larger purpose and the internal academic culture that will bolster their drive to become among the best and most influential universities in the world.